Abstract 13750: Cardiac Resynchronization Therapy for Patients With Cardiac Sarcoidosis

Objective: Little is known about the clinical features in patients with cardiac sarcoidosis who receive cardiac resynchronization therapy (CRT). We aimed to clarify the clinical response to CRT in patients with cardiac sarcoidosis. Methods: We compared the clinical data on CRT between heart failure patients with cardiac sarcoidosis and those with other etiologies at 3 cardiovascular centers. The primary endpoint was composite outcome of cardiovascular death or hospitalization from worsening heart failure within 5 years after the CRT. Results: The patients with cardiac sarcoidosis (N=18) were more likely than those without cardiac sarcoidosis (N=141) to be female (83.3% vs. 22.7%; P<0.001), and undergo an upgrade from a pacemaker or implantable cardioverter defibrillator (72.2% vs. 18.4%; P<0.001). The composite outcome occurred with a similar frequency (38.9% vs. 48.2%; P=0.37). The patients with cardiac sarcoidosis were more likely than those without to have sustained ventricular arrhythmias occurring be...