Sebaceous gland hyperplasia of the vulva.

Abstract BACKGROUND: Sebaceous gland hyperplasia is a common condition of the face in elderly patients. We report a case of sebaceous gland hyperplasia on the vulva. CASE: A 19-year-old woman presented with a polypoid tumor on her left labium majus of which the greatest diameter was 2.5 cm, covered by normal appearing skin. Histologic examination revealed a sebaceous gland hyperplasia. Immunohistochemical techniques showed high expression of androgen receptors on sebaceous cells. CONCLUSION: Clinical and gross features of the two documented cases of sebaceous gland hyperplasia on the vulva are different from those of typical lesions on the face. Histologic study of a vulvar biopsy is required to reach a specific diagnosis of this hamartomatous benign condition.