Effects of controlled ovarian stimulation on toxicity of TAC chemotherapy in early breast cancer patients

Stefanie de Groot,Leoni A. Louwé,Ashna Ie Ramautar,J.E.A. Portielje,Aernout C. Ogilvie,Erdogan Batman,Marta Fiocco,Judith R. Kroep

Effects of controlled ovarian stimulation on toxicity of TAC chemotherapy in early breast cancer patients

2018

Stefanie de Groot
Leoni A. Louwé
Ashna Ie Ramautar
J.E.A. Portielje
Aernout C. Ogilvie
Erdogan Batman
Marta Fiocco
Judith R. Kroep

Background Oocyte and embryo cryopreservation, using controlled ovarian stimulation (COS), are common fertility preservation methodologies in breast cancer patients receiving gonadotoxic neo (adjuvant) chemotherapy (CT). The effects of COS and peak estradiol levels on CT-induced side effects are unknown.

Keywords:

Breast cancer
Stimulation
Toxicity
Cancer research
Chemotherapy
Medicine
Controlled ovarian hyperstimulation
Gastroenterology
Cyclophosphamide
Internal medicine
Mucositis
Fertility preservation
Docetaxel

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