Magnetic Resonance Imaging Compatible Biomaterials For Realization of Interventional Operations

Realization of interventional therapeutic procedures with guidance of Magnetic Resonance Imaging (MRI) is a promising novelty in area of interventional surgery because of eliminating x-ray exposure to patient body. Together with radiation free nature, advances in MRI techniques present superior soft tissue contrast and real time physiologic parameters from related tissue. However, the strong static magnetic field, magnetic radiofrequency (RF) pulses, and time-varying gradient fields applied during MRI, may result in exceeded heating risk over interventional instruments and adjacent tissue inside patient body. Additionally, since real time tracking and determination of device position inside patient body is critical for operators, sufficient visibility under MRI is another challenging issue to overcome. Therefore, proper biomaterials must be utilized for designing and development of MRI compatible interventional instruments by considering many factors including biocompatibility, MRI safety, MRI visibility, and other mechanical needing.