Effect of hyperthyroidism on antral myoelectrical activity, gastric emptying and dyspepsia in man

Background/Aims: The objective of the present study was to investigate the effect of hyperthyroidism on antral myoelectrical activity, gastric emptying and dyspepsia in man. Methodolgy: Twenty-three patients with manifest hyperthyroidism and dyspepsia confirmed by a standardized protocol were studied by electrogastrography (EGG). The following EGG parameters were determined : dominant frequency (DF cycles per minute (cpm), DF (%) in the normal range (2-4 cpm)), bradygastria ( 68%). However, these patients did not differ in tachygastria and the other EGG parameters from those with normal gastric emptying (p >0.05). Both EGG and radioscintigraphy did not correlate significantly with dyspepsia. Conclusions: Dyspeptic patients with hyperthyroidism frequently display tachygastria and delayed gastric emptying. However, tachygastria has no important effect on gastric motor activity in hyperthyroidism.