Recommendations for the treatment of invasive fungal infection caused by filamentous fungi in the hematological patient

2011 
espanolEl tratamiento antifungico del paciente hematologico ha alcanzado una gran complejidad con la llegada de nuevos antifungicos y pruebas diagnosticas que han dado lugar a diferentes estrategias terapeuticas. La utilizacion del tratamiento mas adecuado en cada caso es fundamental en infecciones con tanta mortalidad. La disponibilidad de recomendaciones como estas, realizadas con la mejor evidencia por un amplio panel de 48 expertos, en las que se intenta responder a cuando esta indicado tratar y con que hacerlo considerando diferentes aspectos del paciente (riesgo de infeccion fungica, manifestaciones clinicas, galactomanano, TC de torax y profilaxis realizada), puede ayudar a los clinicos a mejorar los resultados. EnglishAntifungal treatment in the hematological patient has reached a high complexity with the advent of new antifungals and diagnostic tests, which have resulted in different therapeutic strategies. The use of the most appropriate treatment in each case is essential in infections with such a high mortality. The availability of recommendations as those here reported based on the best evidence and developed by a large panel of 48 specialists aimed to answer when is indicated to treat and which agents should be used, considering different aspects of the patient (risk of fungal infection, clinical manifestations, galactomanann test, chest CT scan and previous prophylaxis) may help clinicians to improve the results.
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