Glimepiride medicinal composition tablets and preparation method and application thereof

The invention provides glimepiride medicinal composition tablets. The glimepiride medicinal composition tablets are characterized by comprising the following components: glimepiride and chromium picolinate, wherein the weight ratio of the glimepiride to the chromium picolinate is (10-80): (1-100). A glimepiride Chinese herbal medicine and the chromium picolinate are taken as active ingredients; and compared with the conventional glimepiride preparation, the invention has the advantages that: the medicinal composition improves the sensitivity and activity of peripheral tissues to insulin, and the chromium picolinate can also improve the endurance capacity of organisms to glucose and reduce the blood sugar level after abrosia, so the glycometabolism of the organisms can be improved. Excess glucose in a human body can be converted into fat, so that the metabolism of the glucose can be effectively improved, the metabolism of the fat is indirectly regulated, the deposition of the fat in the human body is reduced, and the levels of total glycerin (TG), low-density lipoprotein (LDL) and total cholesterol are reduced. The function of the insulin is improved to affect the metabolism of saccharides, lipids, protein, nucleic acid and the like.