Improvement in patient-reported outcomes in Chinese adults after bariatric surgery: 1-year follow-up of a prospective cohort

Abstract Objective To assess changes of patient-reported outcomes in terms of health-related quality of life (HRQOL), depression, anxiety status and physical activity (PA) after bariatric surgery among patients with obesity. Settings Queen Mary Hospital, Tung Wah Hospital and United Christian Hospital, Hong Kong SAR; a longitudinal study. Methods A multi-center prospective observational cohort was conducted in Hong Kong between 2017 and 2018. Follow-up interviews at 1-month, 3-month, 6-month and 12-month postoperatively were administrated via telephone. Short Form-12 Health Survey Version 2 (SF-12v2), Euroqol 5-dimension-5-level (EQ-5D-5L) and Impact of Weight on Quality of Life-Lite (IWQOL-Lite) were utilized to assess HRQOL. Scores of anxiety and depression were evaluated by Hospital Anxiety and Depression Scale (HADS). Walking, moderate and vigorous metabolic equivalent tasks (MET) and PA levels were measured by International Physical Activity Questionnaire-Short Form (IPAQ-SF). Demographic and clinical characteristics including age, gender, body mass index and pre-existing comorbidities at baseline were collected. Comparisons of scores were made between baseline and 12 months using paired t-test or McNemar test. Results A total of 25 patients who have received bariatric surgery (Laparoscopic sleeve gastrectomy: 96%; laparoscopic gastric bypass: 4%) and 25 control patients matched using propensity scores derived by baseline covariates were involved. Significant improvements were observed in HRQOL regarding physical functioning (P Conclusion After 12 months of follow-up, increase in physical quality of life, reduction in depression status and less impairment caused by weight were observed, without significant changes in anxiety score and postoperative PA.