Microanatomical organization and cytoarchitectonics of lymphoid tissue in the mesenteric lymph nodes under conditions of experimental total hyperthermia

: Microanatomical organization and cell composition of the rat mesenteric lymph nodes have been studied under conditions of experimental total hyperthermia. Possibilities of the compensatory-adaptive reactions of the lymphoid tissue have been determined. Disturbances of microhemo-++- and lymphocirculation in the lymph nodes in different time after hyperthermia are accompanied with accumulation of mast cells and eosinophils in various zones of the node; they normalize certain physiological parameters of microcirculation and permeability of the metabolic microvessel walls. In 30 days after a single total overheating of the rat organism, the microanatomical organization changes in the lymph nodes investigated are manifested as atrophy of B-dependent zones and further volumetric increase of the paracortical zone. Therefore, it is possible to think about a decreasing intensity of the humoral immunity and increasing intensity of the cellular one.