Enhanced oral bioavailability and hepatoprotective activity of thymoquinone in the form of phospholipidic nano-constructs

Charul Rathore,Navneet Kumar Upadhyay,R. Kaundal,R.P. Dwivedi,Sameer S. Rahatekar,A. John,Kamal Dua,Murtaza M. Tambuwala,S Jain,D. Chaudari,Poonam Negi

Enhanced oral bioavailability and hepatoprotective activity of thymoquinone in the form of phospholipidic nano-constructs

2020

Charul Rathore
Navneet Kumar Upadhyay
R. Kaundal
R.P. Dwivedi
Sameer S. Rahatekar
A. John
Kamal Dua
Murtaza M. Tambuwala
S Jain
D. Chaudari
Poonam Negi

ABSTRACTBackground: The poor biopharmaceutical properties of thymoquinone (TQ) obstruct its development as a hepatoprotective agent. To surmount the delivery challenges of TQ, phospholipid nanocons...

Keywords:

Pharmacology
Nano-
Box–Behnken design
Materials science
Bioavailability
Thymoquinone
Pharmacokinetics
Biopharmaceutical
Hepatoprotective Agent

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