Detection of a processed pseudogene of the human MBL-associated serine protease, MASP1.

ABC Fax + 41 61 306 12 34 E-mail karger@karger.ch www.karger.com © 2002 S. Karger AG, Basel 0301–0171/02/0981–0108$18.50/0 Accessible online at: www.karger.com/cgr Abstract. Southern hybridization analysis of the MASP1 gene using an intron-specific probe detected a single band. An exon-specific probe detected several bands. PCR of genomic DNA using several exon-specific primer sets of MASP1 produced short and long products. Sequence of the shorter products corresponded to the processed pseudogene of MASP1. By fluorescence in situ hybridization, this pseudogene (MASP1P1) was mapped to 1p34.