Avaliação da atividade antiviral e determinação do perfil cromatográfico de Hippeastrum glaucescens (Martius) Herbert (Amaryllidaceae)

Evaluation of antiviral activity and determination of the chromatographic profile of Hippeastrum glaucescens (Martius) Herbert (Amaryllidaceae). Plants of Amaryllidaceae are characterized by isoquinoline alkaloids. Since the first study with Amaryllidaceae alkaloids in 1877, a large number of these plants have been chemically investigated. These compounds have shown a wide range of biological activities such as: antiviral, cytotoxic, antitumoral and analgesic. In this work, the dichloromethane (CH 2 Cl 2 ) extracts obtained from different parts of the Hippeastrum glaucescens (Martius) Herbert (bulbs, roots, leaves and flowers) and the isolated alkaloids lycorine, tazettine and pretazettine were analyzed by a chromatographic method (TLC) and tested for antiviral activity. The