DNA hypomethylation within specific transposable element families associates with tissue-specific enhancer landscape

Mingchao Xie,Chibo Hong,Bo Zhang,Rebecca F. Lowdon,Xiaoyun Xing,Daofeng Li,Xin Zhou,Hyung Joo Lee,Cecile L. Maire,Keith L. Ligon,Philippe Gascard,Mahvash Sigaroudinia,Thea D. Tlsty,Theresa A. Kadlecek,Arthur Weiss,Henriette O'Geen,Peggy J. Farnham,Pamela A. F. Madden,Andrew J. Mungall,Angela Tam,Baljit Kamoh,Stephanie Cho,Richard A. Moore,Martin Hirst,Marco A. Marra,Joseph F. Costello,Ting Wang

DNA hypomethylation within specific transposable element families associates with tissue-specific enhancer landscape

2013

Introduction—Transposable element (TE) derived sequences comprise half of our genome and DNA methylome, and are presumed densely methylated and inactive. Examination of the genome

Keywords:

DNA hypomethylation
Transposable element
Enhancer
DNA
DNA methylation
Genetics
Histone
Genome
Epigenomics
Molecular biology
Biology

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