TAH and BSO with adjuvant pelvic EXRT and vaginal Cs-137 boost in the management of carcinoma of the endometrium.

: Combined surgery and radiation has become standard therapy for operable endometrial cancer patients with stage IA (grade 2-3 or deep muscle invasion), stage IB, stage II, and selected stage III disease. We discuss the rationale for whole pelvic external-beam radiation therapy (EXRT) followed by vaginal endocurietherapy (ECT) boost, and present the outcome of 43 patients with endometrial cancer treated by combined surgery and radiation.