Underwater Leidenfrost nanochemistry for creation of size-tailored zinc peroxide cancer nanotherapeutics

Water can function as a sustainable reactor for the synthesis of size-controlled, functional nanoparticles. Here, the authors introduce an underwater Leidenfrost synthesis that reproduces the dynamic chemistry of the deep ocean, in which anticancer therapeutic ZnO2 nanoclusters form in an overheated zone and migrate to colder water to continue growth.