Comparative vasoconstrictor effects of inhaling tobacco smoke in warm and cool environments and before and after abstinence from tobacco

Abstract It is generally agreed that the inhalation of tobacco smoke causes vasoconstriction in the foot. 1 However, quantitative data concerning the relative intensity of this vasoconstriction are not available. The experiments described herein were designed to compare foot blood flow responses to smoking under different control conditions of vasomotor activity, to compare the vasoconstrictor response to smoking with that produced by a cool environment and to determine whether or not a period of abstinence from tobacco results in a more profound vasoconstrictor response to smoking.