Intracranial aneurysm: experience in treating 649 patients

Objective To explore risk factors for the development of intracranial aneurysms,and the selection of therapeutic methods for unruptured intracranial aneurysms. MethodWe retrospectively reviewed the data of the treatment of 649 patients, including clipping of aneurysm 535 cases (82. 4%), isolation of aneurysm 19 cases (2. 9%), and coating of the aneurysm 17 cases (2. 6%), endovascular treatment 46 cases (7. 1%) ,follow up symptomless patients 32 cases(5%). Results 12 cases died after operation, the overall operative mortality was 1.9%. We identified hypertension, female sex, advanced age, and smoking as significant risk factors for sporadic intracranial aneurysms. Conclusions Hypertension,female, sex, advanced age, and smoking are significant risk factors for sporadic intracranial aneurysms. Follow up is a good choice for some symptomless patients. Key words: Intracranial aneurysm;  Treatment;  Risk factors;  Unruptured intracranial aneurysms;  Follow up