Profile and Outcomes of Surgical Treatment for Ventricular Septal Rupture in Patients with Shock

Abstract Background The outcomes of surgical treatment of ventricular septal rupture complicating acute myocardial infarction are worse in patients with cardiogenic shock.This study aimed to identify clinical characteristics and outcomes in patients with ventricular septal rupture presenting with cardiogenic shock. Methods A retrospective analysis was performed in 105 consecutive ventricular septal rupture patients, 71with cardiogenic shock (67.6%) and 34 without cardiogenic shock (32.4%), who underwent surgical treatment in the Department of Adult Cardiac Surgery of Fuwai Hospital between January 2002 and December 2017. Baseline characteristics and outcomes in patients with ventricular septal rupture with and without cardiogenic shock were assessed. Results There were no differences in hypertension, diabetes, history of myocardial infarction, body mass index, or location of ventricular septal rupture between patients with and without cardiogenic shock. The size of ventricular septal rupture was larger in patients with cardiogenic shock than in those without (18.2±8.1 mm vs. 14.0±7.8mm, p=0.013). Intraaortic balloon counterpulsation was required more in patients with cardiogenic shock before operation [39 (68.4%) vs 1(5.0%), p Conclusions The larger the ventricular septal rupture, the more prone patients are to develop cardiogenic shock. Surgical treatment outcomes for ventricular septal rupture with cardiogenic shock are satisfactory.