Genotoxic and antiproliferative potential of extracts of Echinodorus grandiflorus and Sagittaria montevidensis (Alismataceae)

AbstractThe economic potential of the germplasm of medicinal species is a rich resource that should be preserved and used. The medicinal species Echinodorus grandiflorus and Sagittaria montevidensis belong to the family Alismataceae. Depurative, diuretic, anti-inflammatory, antivenin, and anti-rheumatic actions have been associated with E. grandiflorus, where the leaves are the main part used. Sagittaria montevidensis does not yet have its medicinal properties known and has a wide morphological variability, and is sometimes confused with E. grandiflorus. The present study aimed to evaluate the genotoxic and antiproliferative potential of extracts of dry leaves of E. grandiflorus and S. montevidensis on the cell cycle of Allium cepa, as well as undertake analysis by high performance liquid chromatography (HPLC-DAD) for the quantification of the compounds from the extracts. A. cepa bulb rootlets were submitted to the extracts for 24 h, prepared from plant material at two concentrations, 6 g dm−3 and 24 g dm...