5-hydroxymethylcytosine as a liquid biopsy biomarker in mCRPC.

Martin Sjostrom,Zhao Shuang G,Eric J. Small,Yuhong Ning,Corinne Maurice Dror,Adam Foye,Jun Jie T. Hua,Haolong Li,Tomasz M. Beer,Christopher P. Evans,Matthew Rettig,Kim N. Chi,Joshi J. Alumkal,Rahul Aggarwal,Alan Ashworth,Samuel Levy,Housheng Hansen He,Alexander W. Wyatt,David A. Quigley,Felix Y. Feng

5-hydroxymethylcytosine as a liquid biopsy biomarker in mCRPC.

2021

148Background: 5-hydroxymethylcytosine (5hmC) is an epigenetic modification which regulates gene expression and is associated with active transcription. The optimization of 5hmC sequencing in cell-...

Keywords:

Cancer research
Gene expression
Biomarker (medicine)
Epigenetics
Liquid biopsy
Transcription (biology)
Medicine
5-Hydroxymethylcytosine

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