Relation between lymphocyte to monocyte ratio and short-term mortality in patients with acute pulmonary embolism.

Introduction The relationship between inflammation and mortality after acute pulmonary embolism (APE) has previously been investigated with different variables (platelet/lymphocyte ratio, etc). Objectives We investigated the predictive value of lymphocyte to monocyte ratio (LMR) for mortality in first 30 days after APE. Methods The study population included 264 APE patients of which 230 patients were survivors, 34 patients were non-survivors. Results LMR was significantly lower in non-survivors after APE (P < .001). Neutrophil-to-lymphocyte ratio (NLR) was higher in non-survivors after APE (P < .001). Platelet-to-lymphocyte (PLR) had no significance between both groups (P: .241). Simplified pulmonary embolism severity index and LMR were independent predictors of mortality in patients with APE (P: .008 and P: .001, respectively). Conclusion LMR as a novel marker of inflammation seemed to be an independent predictor of short-term mortality in patients with APE.