A kind of Apixaban tablet and preparation method thereof

The present invention provides a kind of Apixaban tablet, contain Eliquis raw material and pharmaceutic adjuvant, the X ray powder diffractions that wherein Eliquis raw material is represented with 2 θ angles are at 12.8 ± 0.2 °, 13.9 ± 0.2 °, 17.0 ± 0.2 °, 18.4 ± 0.2 °, 22.2 ± 0.2 °, there is characteristic peak at 26.9 ± 0.2 °, present inventors have unexpectedly found that, when by the D of Eliquis A crystal formations 90 At 40 85 μm, obtained Eliquis preparation dissolution rate change is very small, and dissolution rate is hardly changed by the change of particle diameter, has obtained the homogeneous Eliquis preparation of dissolution for control.