Do Sepsis-3 criteria facilitate earlier recognition of sepsis and septic shock? A retrospective cohort study

ABSTRACTBackground:New Sepsis-3 criteria are supposed to “facilitate earlier recognition … of patients with sepsis.” To test this, we performed novel and direct comparisons of Sepsis-1 vs. Sepsis-3 criteria with respect to time differences of sepsis onset.Methods:In a cohort of intensive care unit (