68Ga MPO Platelets in Human Pet Thrombus Imaging

The excellent immediate results of various interventional techniques for recanalization of peripheral and coronary arterial lesions has highlighted the persistant problem of restenosis, occurring in as many as 30% of patients in 1 year and 66% in 2 years1. Platelet deposition and its sequellae are among the most important possible causes of restenosis, and intensive research on the prevention of restenosis has involved many new anti-platelet drugs2. A method of measuring platelet deposition in vivo, would better define the effectiveness of the various anti-platelet protocols, help select patients and permit monitoring of anti-platelet drug activity3.