Preparation method of fidaxomicin crystal

The invention discloses a fidaxomicin crystal and a preparation method of the crystal. Characteristic peaks, expressed by 2 theta, of an X-ray powder diffraction spectrum of the crystal are located at 3.324, 7.745, 9.989, 1.607, 13.954, 14.475, 15.355, 15.855, 18.800, 19.999, 20.321, 22.245, 23.104, 24.028 and 24.446. The method comprises the preparation steps of dissolving fidaxomicin in an aqueous solution of alcohol, crystallizing, conducting suction filtration, drying, and obtaining the fidaxomicin crystal. The preparation method has the advantages that the preparation method is stable in process and simple and quick to operate, facilitates environmental protection, and is appropriate to industrial production. The obtained fidaxomicin is stable in crystal form and uniform in particle, and facilitates subpackage and storage.