Crotalus horridus horridus Venom-Induced Thrombocytopenia: Characterization of Venom after Binding of Crotalidae Polyvalent Immune Fab Antivenom

However, we observed large interindividual variability. Between 2860 m and 3400 m, the majority (60%, n 1⁄4 284) of NTN SBPs did not change, while 21% (n 1⁄4 102) increased 410 mm Hg and 19% (n 1⁄4 91) decreased 410 mm Hg. The pattern was similar in NTNs between 3400 m and 4300 m: (65% [n 1⁄4 202] no change, 21% [n 1⁄4 65] increased, 15% [n 1⁄4 46] decreased). A greater proportion of HTN trekkers had SBP decreases between 2860 m and 3400 m (45% [n 1⁄4 19] no change, 19% [n 1⁄4 8] increased, 36% [n 1⁄4 15] decreased) and between 3400 m and 4300 m (44% [n 1⁄4 10], 26% [n 1⁄4 6], 30% [n 1⁄4 7]), respectively. Conclusions.—In most individuals, with and without HTN, BP is likely to change less than 10 mm Hg at altitudes up to 4300 m. In general, travelers, including those with well-controlled HTN, may be reassured that their blood pressure will remain relatively stable at high altitude. Funding: WMS Hultgren Grant (2014).