Nodular Epiretinal Gliosis in the Fovea.

Abstract To describe a peculiar hyperreflective optical coherence tomography finding of nodular epiretinal gliosis at the fovea that may be a manifestation of Muller response to retinal injury. The central fovea is stabilized by the Muller cell cone but is at risk of foveal dehiscence due to various insults including vitreomacular traction which can lead to lamellar or full thickness macular hole formation. 1 Degenerative lamellar macular holes can be associated with epiretinal proliferation which has been attributed to activated Muller cells. 2 In this report, we describe a very unusual optical coherence tomography (OCT) finding of nodular epiretinal gliosis which may be the result of Muller cell activation and expansion.