Expression and significance of livin and Fas/FasL in lung cancer

Livin and Fas-FasL can inhibit cell apotosis. Recent studies show Livin is overexpressed in lung cancer and promotes tumor development. Fas -FasL is expressed abnormally in lung cancer. Aberrant expression of Livin and Fas-FasL may play synergetic roles in lung carcinogenesis, and may be new targets for diagnosis and gene treatment of lung cancer. Key words: Lung neoplasms ;  Apoptosis ;  Suppressor factors ;