Antibodies to carbamylated α-enolase epitopes in rheumatoid arthritis also bind citrullinated epitopes and are largely indistinct from anti-citrullinated protein antibodies

Evan Reed,Xia Jiang,Nastya Kharlamova,A. Jimmy Ytterberg,Anca Irinel Catrina,Lena Israelsson,Linda Mathsson-Alm,Monika Hansson,Lars Alfredsson,Johan Rönnelid,Karin Lundberg

Antibodies to carbamylated α-enolase epitopes in rheumatoid arthritis also bind citrullinated epitopes and are largely indistinct from anti-citrullinated protein antibodies

2016

Evan Reed
Xia Jiang
Nastya Kharlamova
A. Jimmy Ytterberg
Anca Irinel Catrina
Lena Israelsson
Linda Mathsson-Alm
Monika Hansson
Lars Alfredsson
Johan Rönnelid
Karin Lundberg

Background: In addition to anti-citrullinated protein antibodies (ACPAs), antibodies targeting carbamylated (i.e., homocitrullinated) proteins (anti-CarP antibodies) have been described in rheumato ...

Keywords:

Epitope
Anti–citrullinated protein antibody
Anti-nuclear antibody
Antibody
Immunology
Autoantibody
Rheumatoid arthritis
Cross-reactivity
Enolase
Medicine
Internal medicine
Rheumatology

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