miR-21 is a key therapeutic target for renal injury in a mouse model of type 2 diabetes

Xiang Zhong,Arthur C.K. Chung,Hai-Yong Chen,Yuan Dong,Xiaoming Meng,Rong Li,Weiqin Yang,Fan Fan Hou,Hui-Yao Lan

miR-21 is a key therapeutic target for renal injury in a mouse model of type 2 diabetes

2013

Xiang Zhong
Arthur C.K. Chung
Hai-Yong Chen
Yuan Dong
Xiaoming Meng
Rong Li
Weiqin Yang
Fan Fan Hou
Hui-Yao Lan

Aims/hypothesis As microRNA-21 (miR-21) plays a pathological role in fibrosis, we hypothesised that it may be a therapeutic target for diabetic nephropathy.

Keywords:

Fibrosis
Diabetic nephropathy
Type 2 diabetes
Diabetes mellitus
Biology
Endocrinology
Internal medicine
renal injury
tgf β signalling
human physiology
Pathological

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