Infrared monitoring of the dynamics of the local temperature as a symptom of adaptation to hypoxia and efficiency of antihypoxic drugs

The literature review shows that the general body temperature and the local temperature of individual organs of humans and animals have a significant impact on their reaction to the lack of arterial blood, oxygen and anti-hypoxic and anti-ischemic agents. It is shown that human and animal body organs have different resistance to hypoxia. The least resistant to ischemia and hypoxia is the brain, and it is the first hypoxia damaged cerebral cortex. It is shown that with a lack of oxygen, the death of neurons in the brain can be effectively prevented by timely administration of oxygen to the brain and/or lowering its local temperature. However, to date, no technologies have been developed that provide an immediate increase in the concentration of oxygen and/or a decrease in the local temperature in the brain of people while maintaining their performance. Under these conditions, professor V.M. Vinogradov proposed to find the possibility of extending the life of brain cells in conditions of lack of oxygen using drugs that have been called antihypoxants. Technologies of infrared diagnostics of hypoxia, estimation of reserves of adaptation to it and ways of estimation of efficiency of antihypoxants are described.