Primary pulmonary T-cell lymphoma: a case report.
2010
Primary pulmonary T-cell lymphoma is an extremely rare malady, and we diagnosed this in a 52-year-old male who was admitted to our hospital with cough for the previous two weeks. The chest CT demonstrated multiple variable sized mass-like consolidations with low density central necrosis in the peripheral portion of both the upper and lower lobes. Positron emission tomography (PET) showed multiple areas of hypermetabolic fluorodeoxyglucose (FDG) uptake in both lungs with central metabolic defects, which correlated with central necrosis seen on CT. The histological sample showed peripheral T-cell lymphoma of the not otherwise specified form. The follow-up CT scan showed an increased extent of the multifocal consolidative lesions despite that the patient had undergone chemotherapy. rimary lymphoma of the lung is a rare disorder, and primary pulmonary lymphoma represents only 0.5-1% of all primary pulmonary malignancies, less than 1% of all the cases of non-Hodgkin’s lymphoma (NHL) and 3-4% of all the extranodal manifestations of NHL (1). Most of the cases of the primary lymphoma of the lung originate from the B-cell lineage, and the disease is frequently located in the bronchus-associated lymphoid tissue. Very few cases of pulmonary T-cell lymphoma have been reported and the imaging features of this rare cancer have not been well characterized. We report here on an extremely rare case of primary pulmonary peripheral T-cell lymphoma not otherwise specified (PTCLN), and we present the CT and positron emission tomography (PET) images.
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