Abstract 442: Combined Drug Therapy With an Angiotensin Type 1 Receptor Antagonist and Neprilysin Inhibitor Lowers Angiotensin II-induced Atherosclerosis, But Not Abdominal Aortic Aneurysms in Hyperlipidemic Male Mice

Sean E. Thatcher,Jenny Liang,Yasir Alsiraj,Mark Ensor,Heba Ali,Victoria L. English,Lisa A. Cassis

Abstract 442: Combined Drug Therapy With an Angiotensin Type 1 Receptor Antagonist and Neprilysin Inhibitor Lowers Angiotensin II-induced Atherosclerosis, But Not Abdominal Aortic Aneurysms in Hyperlipidemic Male Mice

2020

Sean E. Thatcher
Jenny Liang
Yasir Alsiraj
Mark Ensor
Heba Ali
Victoria L. English
Lisa A. Cassis

Objective: Angiotensin II (AngII) actions at angiotensin type 1 receptors (AT1R) contribute to the development of atherosclerosis and abdominal aortic aneurysms (AAAs), two vascular diseases exhibi...

Keywords:

male mice
Renin–angiotensin system
Aortic aneurysm
Pharmacotherapy
Receptor
Pharmacology
Neprilysin
Medicine
Receptor antagonist
Angiotensin II

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