LYMPHOCYTE APOPTOSIS : MECHANISM OF SPECIFIC IMMUNOTHERAPY OF ATOPIC DISEASES

Effect of specific immunotherapy on the expression of activation markers, apoptosis marker CD95, and peripheral blood lymphocyte morphology were studied in patients with atopic bronchial asthma. Specific therapy activated T and B cells and triggered lymphocyte apoptosis. Apoptosis may play an important role in induction of allergen tolerance during specific therapy.