Anxiolytic Activity of Diterpene Alkaloid Songorine

Yu. V. Nesterova,T. N. Povet’eva,N. I. Suslov,E. E. Shults,G. N. Ziuz’kov,S. G. Aksinenko,O. G. Afanas’eva,A. V. Krapivin,T. G. Kharina

Anxiolytic Activity of Diterpene Alkaloid Songorine

2015

Yu. V. Nesterova
T. N. Povet’eva
N. I. Suslov
E. E. Shults
G. N. Ziuz’kov
S. G. Aksinenko
O. G. Afanas’eva
A. V. Krapivin
T. G. Kharina

Antianxiety action of diterpene alkaloid songorine was studied using Vogel conflict test. Songorine in a dose of 0.25 mg/kg demonstrated high anxiolytic activity comparable to that of phenazepam and produced no sedative effect.

Keywords:

Aconitum
Diterpene
Sedative
Endocrinology
Anxiolytic
Alkaloid
Traditional medicine
Anti-Anxiety Agents
Internal medicine
Vogel Conflict Test
Phenazepam
Biology
sedative effect

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