Abstract 18920: Post-Translational Modification of Telomeric Repeat-Binding Factor 2 (terf2)-Interacting Protein (terf2ip) Mediates Atherosclerosis (as) via Orchestrating Endothelial Cells (ec) Senescence (sen) and Inflammation

Nhat Tu Le,Kyungsun Heo,Kyung Ae Ko,Tamlyn Thomas,Keigi Fujiwara,Jun Ichi Abe

Abstract 18920: Post-Translational Modification of Telomeric Repeat-Binding Factor 2 (terf2)-Interacting Protein (terf2ip) Mediates Atherosclerosis (as) via Orchestrating Endothelial Cells (ec) Senescence (sen) and Inflammation

2016

Nhat Tu Le
Kyungsun Heo
Kyung Ae Ko
Tamlyn Thomas
Keigi Fujiwara
Jun Ichi Abe

Objective: Shortened telomere (TL) provokes EC Sen, which is associated with focalized EC inflammation and plaque formation in the area exposed by disturbed flow (d-flow). Although it is well known...

Keywords:

Cardiology
Telomere
Internal medicine
Inflammation
Diabetes mellitus
Senescence
Cell biology
Posttranslational modification
TERF2
Medicine
Telomeric-Repeat Binding Factor
disturbed flow

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