Convenient synthesis of 1,2,3,4-tetrahydroquinolines via direct intramolecular reductive ring closure
2006
Abstract A simple and convenient procedure for the synthesis of 3-aryl-1,2,3,4-tetrahydroquinolines is reported. 3-Aryl-1,2,3,4-tetrahydroquinolines are directly obtained by reductive ring closure of 2-phenyl-3-(2-nitrophenyl)-propionitrile derivatives in moderate to high yields.
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