Pluripotent anti-inflammatory immunomodulatory effects of papaverine against cerebral ischemic-reperfusion injury

Abstract The mechanism of the papaverine (PV) for the treatment of cerebral ischemia remains unclear. A total of 42 mice with induced focal cerebral ischemia were randomly divided into three groups: PV,baicalin (BA)and vehicle group. Both PV and BA could significantly reduce the ischemic infarct volume (P