Effect of transection and pacing on human jejunal pacesetter potentials

Abstract The aim of this study was to determine whether transection and pacing alter the frequency of the human jejunal pacesetter potentials (PPs). In 8 patients undergoing Roux gastrectomy, three temporary bipolar electrodes were implanted on the jejunal seromuscularis at sites 5 cm proximal to and 10 and 20 cm distal to the jejunal transection. Three other patients not undergoing Roux transection (controls) had electrodes applied at similar sites. After recovery, the mean ± SEM frequency of the jejunal PPs in Roux patients was slightly slower distal to the jejunal transection (11.0 ± 0.2 cpm) than proximal to the transection (11.3 ± 0.2 cpm, p