Course of immunoglobulins G and M in seriously burned patients

: IgM and IgM levels were measured in 108 burn patients. A marked decrease was evident in these immunoglobulins. The initial fall of IgG can be attributed to the loss of serum via the body surface, i.e. burn blisters. The loss of IgM may be taken as indication of the catabolic phase. Quantitative substitution was possible in almost all cases.