Color OCT: Combined Optical Coherence Tomography and RGB Imaging Through a Double-Clad Fiber Coupler

Optical coherence tomography (OCT) is a powerful interferometric imaging modality for assessing the depth-resolved structure of biological samples [1]. The technology's compatibility with fiber technology has allowed its miniaturization into sub-millimeter endoscopic probes, which has allowed imaging of internal organs and tissues that were previously inaccessible [2]. Furthermore, through its ability to resolve sub-surface morphological features, endoscopic OCT has the potential to expand diagnostic and biopsy guidance capabilities in comparison to standard video endoscopy practices. It has notably been applied to endoscopy in gastroenterology, pulmonology and cardiology.