Phase II trial of palbociclib in recurrent RB-positive anaplastic oligodendroglioma: A Spanish group for research in neurooncology (GEINO) trial.

Juan M. Sepulveda-Sánchez,Miguel Gil,Miriam Crespo-Alonso,María Ángeles Vaz Salgado,Elena Vicente,Carlos Mesia Barroso,Ángel Sánchez,Gema Duran,Ramon De Las Penas,José Muñoz Langa,Guillermo Velasco,Aurelio Hernandez-Lain,Amaya Hilario,L Miguel Navarro,Manuel Benavides,Laura Oleaga,Diana Cantero,Yolanda Ruano,Pilar Sánchez-Gómez,Estela Pineda

Phase II trial of palbociclib in recurrent RB-positive anaplastic oligodendroglioma: A Spanish group for research in neurooncology (GEINO) trial.

2019

2038Background: The pRB-dependent cell cycle checkpoint is altered in the vast majority of anaplastic oligodendrogliomas (AO), either by homozygous deletion or by hypermethylation of CDKN2A and/or ...

Keywords:

Palbociclib
RB Positive
Anaplastic oligodendroglioma
Oncology
Pathology
Medicine
Internal medicine
Neurooncology
Cell cycle checkpoint
CDKN2A
Cancer research
Anaplastic oligodendrogliomas

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