Propargylamines formed from three-component coupling reactions catalyzed by silver oxide nanoparticles

An economic, efficient and green silver oxide nanoparticle catalyzed three-component coupling reaction of aldehydes, amines and alkynes was developed. This method provided various propargylamines in moderate to high yield at room temperature in air. The silver oxide nanoparticles could be separated simply and reused without significant decrease of activity.