The HIV prevention cascade: more smoke than thunder?

contrast, despite the steady rise in the proportion of people living with HIV on treatment, the number of new infections among adults has remained stubbornly high, with a modest 4% fall in east and southern Africa over the past 5 years, and an alarming increase of over 50% in eastern Europe and central Asia. So the HIV Prevention 2020 Framework, laid out in this issue 2 by the Global