Study on the mineral composition detection in bone by spatially offset Raman spectroscopy

As a new Raman spectroscopy technology, Spatially Offset Raman Spectroscopy (SORS) can realize the detection of bilayer-and even multilayer-compositions nondestructively and non-invasively, providing the possibility of vivo biological diagnosis. In this paper, the detection of CO32- and PO43- covered by PTFE was realized, which are the main mineral components of bone tissues.