Food-induced Anaphylaxis in Infants and Children

Abstract Background Recent recommendations to introduce peanut products to infants for peanut allergy prevention requires a focused assessment of infant anaphylaxis. Objective This study describes the symptomatology of food-induced anaphylaxis (FIA) in infants ( Methods Retrospective review between June 2015 and June 2017 of children presenting with FIA at a large urban children's hospital emergency department (ED). Results A total of 357 cases of FIA were evaluated: 47 in infants ( 6 years). Infants presented with gastrointestinal (GI) involvement more frequently than any other age group (89% vs 63% [P = .003], 60% [P Conclusion Infants with FIA primarily presented with GI and skin manifestations. Egg was the most common food trigger in infants. Most infants with FIA did not have eczema or a history of food allergy.