THE EFFECTS OF THIOCTAMIDE FOR ALCOHOL DRINKING AS APPEARED ON ELECTRIC FLICKER

By means of Motokawa's Method of electric flicker the authors examined the change in electric flicker values (EFV) of 6 healthy males due to alcohol drinking with and without oral administration of TAS (10mg) one hour in advance. As drinking alcohol, whisky and Japanese wine were chosen. EFV obtained after drinking whisky (40s60cc) increased remarkably, but EFV obtained after whisky drinking combined with TAS administration did not show any marked increase and EFV showing increase, if any, soon returned to the initial value. As to EFV obtained after drinking Japanese wine (120cc, 150cc, 200cc and 300cc), of the 6 subjects, in 2 it increased remarkably, and their EFV after Japanese wine drinking combined with TAS administration showed decrease and returned rapidly to the initial value. In another 2 subjects EFV showed, after increase, only rapid return to the intial value by TAS administration. In the remaining 2 subjects EFV did not show any remarkable effects due to TAS administration, while in the same subjects, administration of TAS showed greater effects against drinking bigger amount of Japanese wine than a little of it, i.e. the larger the amount of alcohol the greater the effect of TAS.