Effect of Differential Exposures of X-Irradiation on Some Hematological Components in Guinea Pigs

The effect of differential exposures of X-irradiation on the growth, mortality and some hematological components in guinea pigs were studied. A total of ninety male guinea pigs were divided into five groups. Group A served as the control. Groups B and E were irradiated with 350 R and 500 R at one time, groups C and D, irradiated 500 Rat two times, i.e. 150 R+350 R; 250 R+250 R, respectively at an interval of 35 days. The results of this study revealed that the mortality in experimental groups B, C, D and E were 40%, 53.33%, 46.67% and 100% respectively. The growth, the cell counts of WBC and RBC, and the concentration of hemoglobin and plasma protein, were inhibited by X-irradiation. Despite of the same dose applied to groups C, D and E, the degree of inhibitory effect on these hematological components. was the most severe in group E, and the next was that in group C. However, the inhibition was more severe in group D than that in group B.