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Nanometer drug preparation device

2015 
The invention discloses a nanometer drug preparation device. The device is composed of a constant sample injector, a direct current high voltage electricity generator, a reactor, a constant temperature electromagnetic stirrer and a central controller; a mixed solution of ingredients for preparing nanometer drugs is spayed into the reactor through the top end of a capillary tube of the constant sample injector; the direct current high voltage electricity generator generates a direct current high voltage electric field between a positive electrode and a negative electrode, and the high voltage electric field generated by the direct current high voltage electricity generator is loaded on the positive electrode and the negative electrode which are located at the upper end and the lower end of the reactor; under the action of the high voltage electric field, the mixed solution is atomized into fine liquid drops, and the liquid drops move downward to enter into solvent in the reactor; under the action of the constant temperature electromagnetic stirrer, the atomized liquid drops form nanometer drug micelles in the solvent, and the nanometer drug micelles are solidified into nanometer drug particles. The nanometer drugs obtained through preparation are even in particle size, the drug loading efficiency, the encapsulation efficiency and the yield coefficient are high, and by adjusting the voltage of the direct current high voltage electric field, the constant sample feeding flow velocity and the concentration of the fed solution, the nanometer drugs with different particle sizes can be prepared.
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