Extended therapeutic window of a novel peptide inhibitor of TRPM2 channels following focal cerebral ischemia.
2016
Introduction
TRPM2 channels have been suggested to play a role in ischemic neuronal injury, specifically in males. A major hindrance to TRPM2 research has been the lack of specific TRPM2 inhibitors. The current study characterized the specificity and neuroprotective efficacy of a novel TRPM2 inhibitor.
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